FNDC5 attenuates obesity-induced cardiac hypertrophy by inactivating JAK2/STAT3-associated inflammation and oxidative stress
Abstract Background Chronic low-grade inflammation and oxidative stress play important roles in the pca display development of obesity-induced cardiac hypertrophy.Here, we investigated the role of Fibronectin type III domain containing 5 (FNDC5) in cardiac inflammation and oxidative stress in obesity-induced cardiac hypertrophy.Methods Male wild-ty